Value of MRI apparent diffusion coefficient for screening prostate cancer

SHANLianqiang; QUSehua; SHIShikui; JIANGXu; YANGXuezhen

Abstract：ObjectiveTo explore the value of 1.5 T magnetic resonance (MRI) apparent diffusion coefficient (ADC) in screening prostate cancer (PCA).MethodsForty patients with PCA were selected from January 2015 to July 2018 in our hospital as PCA group. At the same time, 60 benign prostate lesions were selected as benign group. The patients in two groups were given 1.5 T-MRI examination. The prostate imaging reporting and data system (PI-RADS) scores, anisotropy ADC and eADC values of the two groups were compared.ResultsThe eADC value in group PCA was significantly higher than that in benign group (P<0.05). The difference of PI-RADS score between group PCA and benign group was significant (P<0.05). In the diagnosis of PCA sensitivity, specificity and accuracy, the critical value of the PI-RADS score were 55.00%, 83.33%, 72.00%, and<0.95 mm2/s as the critical value of 85.00%, 75.00%, 79.00%. The PI-RADS score combined with ADC value 95.00%, 70%, 80.00%. The sensitivity of combination of the two was significantly higher than that of the two alone. The accuracy and Youden index were also greater than the two alone.ConclusionThe ADC value of 1.5 T-MRI can be used as an important indicator of PCA screening. It can effectively improve the screening effect of PI-RADS score on PCA. It is worth for further clinical promotion.