Clinical observation of Jiao Ai decoction combined with Mifepristone in the treatment of irregular bleeding after levonorgestrel intrauterine birth control system

MO Tingting; HUANG Jielin; CHEN Muyin

Abstract：Objective To investigate the efficacy of Jiao Ai decoction combined with mifepristone in the treatment of irregular bleeding after levonorgestrel intrauterine system insertion.Methods Sixty patients with irregular vaginal bleeding after installation of the levonorgestrel IUD system due to abnormal uterine bleeding-ovulatory disorders(AUB-O)admitted to our hospital from April 2022 to March 2024 were selected and randomly divided into the control group and combination treatment group,30 cases each.During the treatment with mifepristone given after the installation of the levonorgestrel intrauterine sterilisation system,haemoglobin concentration,adverse reactions,compliance,bleeding time and bleeding volume were compared between the two groups of patients in the experimental and control groups before and after the intervention.Results The overall efficacy rate of the patients in the combination treatment group was significantly higher than that of the control group after treatment,and statistical analysis showed that there was a significant difference between the two groups.In addition,some indicators in the observation group after the intervention,such as haemoglobin concentration,endometrial thickness,bleeding time,bleeding volume and certain hormone levels,showed significant differences compared with the control group,and these differences were also statistically significant.Meanwhile,the overall compliance of the observation group was also significantly higher than that of the control group,and the differences were statistically significant.Conclusion Jiao Ai decoction combined with mifepristone in the treatment of patients with irregular bleeding after levonorgestrel IUD insertion can improve haemoglobin concentration,shorten bleeding time,reduce bleeding volume,and improve patient compliance.