Study on promotion of fibroblast proliferation by triboelectric nanogenerator patch
ZHAO Chaochao
FANG Ju
HUANG Kaiyi
XIE Yiting
YANG Anping
Abstract:Objective A high-performance triboelectric nanogenerator(TENG)patch was constructed to generate electric field for regulating fibroblast proliferation and scratch healing.Methods A TENG with patch type was constructed by improving the material and structure,and a high-intensity electric field was generated by combining with the interdigital electrode for cell proliferation and cell scratch healing of fibroblasts.Results The open circuit voltage of the 4 cm×4 cm TENG patch was 200 V,the short circuit current was 25 μA,and the transfer charge was 35 nC.The proliferation of fibroblasts and the healing of fibroblast scratches were obviously promoted by electric field stimulation,which was formed by 1 V AC voltage output of the TENG combined with interdigital electrode.Conclusion As a new type of bioenergy harvesting device,TENG could convert mechanical energy into electrical energy.The prepared TENG patch acted as an electric field source to regulate cell activity,which provided a powerful support for tissue repair.
Keywords:triboelectric nanogeneratorfibroblasttissue repairelectric field
Publication Date:2024-07-30
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:6( 64-69 )