Effect of Photodynamic Therapy on microvessel density and vasculal endothelial growth factor in the rabbit hepatcocellular carcinoma models
LI Xiang
Abstract：Objective To investigate the effect of photodynamic therapy on the rabbit hepatcocellular carcinoma (HCC)models and its mechanism. Methods The VX 2 tumor cells were planted in the hepatic left central lobe of 15 rabbits. The level of VEGF and MVD was investigated by immunohistochemical staining. Result The level of VEGF and MVD in PDT group were lower than those of the controls (p<0.05) Conclusion photodynamic therapy might obviously decrease the translational level of VEGF and MVD in tumor cells which may be one of the mechanisms of PDT on hepatocellular carcinoma.
Keywords：photodynamic therapyliver tumorrabbit hepatocellular carcinomaVEGF. MVD
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 27-30 )