The effect of Shenfu injection on myocardium ultrastructure in the cardiopulmonary resuscitated New Zealand rabbits
Abstract：Objective To investigate the protection of myocardium ultrastructure affected by Shenfu injection in the cardiopulmonary resuscitated New Zealand rabbits.Methods Sudden cardiac arrest cardiopulmonary resuscitation model were established by the method of clipping in 24 rabbits.They were divided into 3 groups.Group A were injected with SF（2.1 mL/kg）after successful resuscitated while Group B were intravenously injected every 30 min with NS（5 mL） for 3 times successively,and Group C with nothing.The change of MAP were observed during the arrest.The rabbits were killed in 8 hours after successful resuscitation.The myocardium histiocyte and myocardium ultrastructure were observed under microscope.Results The myocardium histiocyte of each group was similar.The myocardium ultrastructure of group B was worse than that of group A,and that of group C had no obvious change.Conclusion SF injection can protect myocardium from sudden cardiac arrest cardiopulmonary resuscitation in New Zealand rabbits.
Keywords：Shenfu injectioncardiac arrestcardiopulmonary resuscitationultrastructuremyocardium
Publication Date：2011-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 23-26 )