Evaluation of an interpretable 12-lead ECG automatic diagnosis model based on deep feature fusion
LU Xueqi
CHEN Huayuan
WU Qiucen
WEN Yaoqi
LIU Guoguang
CHEN Chaomin
Abstract:Objective To enhance the accuracy and reliability of 12-lead electrocardiogram(ECG)automatic diagnosis.Methods Herein we propose a 12-lead ECG automatic diagnosis model based on deep feature fusion(MRHL-ECGNet),which consists of a multi-scale feature extraction front-end,ResNet-34,a global feature mixing module,and a time-series analysis module.The Hyena Hierarchy Convolution Operator was applied to the 12-lead ECG automatic diagnosis task for more efficient capture of long-range dependencies while reducing computational complexity.Integrated Gradients(IG)-based interpretability analysis technology was used to achieve visualization of the decision-making basis of MRHL-ECGNet.The CPSC2018 dataset was used to train and test MRHL-ECGNet,and its performance was assessed using multiple quantitative evaluation indicators and evaluation experiments.Results In the 9-class ECG classification task on the test set,MRHL-ECGNet achieved an accuracy of 0.972,an AUC of 0.983,an F1 score of 0.864,a precision of 0.873,and a recall of 0.857,all surpassing other comparative models.This model only took 0.007 s to output a diagnosis for a single sample on a GPU and 0.156 s on a CPU,with a memory footprint of 67.196 MB.Conclusion The proposed MRHL-ECGNet model demonstrates excellent classification performance in 12-lead ECG automatic diagnosis with a lightweight design and good interpretability,and thus has great potential for clinical application in ECG-aided diagnosis.
Keywords:electrocardiogram automatic diagnosisdeep learningHyena Hierarchy Convolution Operatorinterpretability of model
Publication Date:2026-01-20
Online Publishing Date:2026-01-22(First online date of this platform, not the publication date of the document)
Pages:11( 208-218 )
Journal of Southern Medical University

Journal of Southern Medical University

ISTICPKUCSCD
ISSN:1673-4254
Year, Vol.(Issue):2026,46(1)