Epidemiological survey of osteoporosis in Beijing over the past decade:a single-center analysis of dual-energy X-ray absorptiometry scans from 30 599 individuals
ZHOU Ying
ZHANG Danyang
WU Lifan
WANG Guishan
MU Jiedan
CUI Chengwen
SHI Xiuxiu
DONG Jige
WANG Yu
XU Wangli
LI Xiao
Abstract：Objective To analyze bone mass distribution and the factors affecting bone mass in a general Chinese Han cohort undergoing physical examinations at our center.Methods We retrospectively collected the data of bone mineral density(BMD)measurements from 30 599 healthy Han Chinese adults(age≥20 years)who underwent dual-energy X-ray absorptiometry scans at our hospital from July,2013 to July,2023.Basic parameters including height,body weight,and gender were recorded,and descriptive statistics and correlation analyses were performed using R software.Results In this cohort,the male individuals had a mean peak BMD of 1.00±0.12 g/cm2 in the lumbar vertebrae,0.94±0.14 g/cm2 in the femoral neck,and 0.99±0.13 g/cm2 in the total hip,significantly higher than the values in the female individuals[0.99±0.12 g/cm2 in the lumbar vertebrae(P=0.022),0.79±0.11 g/cm2 in the femoral neck(P<0.001),and 0.88±0.11 g/cm2 in the total hip(P<0.001)].In the overall cohort,the BMD values of the lumbar spine and femur decreased with age after reaching their peak levels.There was a positive correlation between BMD value and body mass index(BMI)in both male and female individuals.The 2013-2014 period recorded the lowest BMD values in the lumbar,hip,and femoral neck,which tended to increase steadily in the following years(2015-2023).Conclusion Our data suggest that the BMD values vary among different populations,and future multi-center studies using more accurate BMD detection technology are warranted to capture the variation patterns of BMD with demographic characteristics of specific populations.
Keywords：bone mineral densityosteoporosisdual-energy X-rayepidemiology
Publication Date：2025-03-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：10( 443-452 )