Multiple arterial grafts does not increase perioperative or short-to medium-term risks of postoperative MACE in patients with impaired left ventricular function:3-year follow-up results
LI Ziru
BAI Shengwei
ZHANG Jian
XU Hao
ZANG Suhua
ZHANG Xin
Abstract：Objective To compare perioperative and mid-term results of multiple versus single arterial off-pump coronary artery bypass grafting(OPCABG)in patients with impaired left ventricular function.Methods This study was conducted among 86 patients with a left ventricular ejection fraction(LVEF)<50%,who underwent OPCABG at our hospital between January,2018 and December,2021.Of these patients,22 underwent OPCABG with multiple arterial grafts(multiple graft group)and 64 received a single arterial graft in OPCABG(single graft group).The preoperative,intraoperative,and perioperative data were collected,and the patients were followed up for a mean of 29.28±14.84 months.The perioperative outcomes and follow-up results of the patients were compared,and the factors influencing major adverse cardiovascular events(MACE)were identified using logistic regression.Kaplan-Meier analysis was used to compare the postoperative survival rate without MACE.Results The patients in multiple graft group had a significantly younger age than those in single graft group(P<0.05),but the other baseline data were similar between the two groups(P>0.05).Perioperative mortality,24-h postoperative drainage volume,length of ICU stay,intubation time,and the incidence of new-onset atrial fibrillation were all similar between the two groups(P>0.05),but the rate of postoperative hypotension was significantly higher in multiple graft group(34.78%vs 11.54%,P=0.009).No significant differences were found in the incidence of MACE or echocardiographic data during the follow-up.Logistic regression identified the female sex(OR:0.191,95%CI:0.049-0.075)and creatinine level(OR:1.016,95%CI:1.000-1.033)as factors affecting postoperative MACE occurrence.Kaplan-Meier analysis showed no significant difference in MACE-free survival rate between the two groups.Conclusion OPCABG with multiple arterial grafts does not increase severe perioperative complications or the risk of mid-term MACE in patients with impaired left ventricular function.
Keywords：coronary artery bypass graftingoff-pumpmultiple arterial graftreduced left ventricular function
Publication Date：2025-02-19
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 239-244 )