Renal arterial spin labeling magnetic resonance imaging in normal adults:a study with a 3.0 T scanner
ZHANG Fan
ZHANG Xuelin
YANG Li
SHEN Jie
GAO Wei
Abstract:Objective To analyze the renal relative blood flow value (rBFV) and image quality in normal adults using single-shot fast spin echo, flow sensitive invention recovery (SSFSE-FAIR) magnetic resonance (MR) sequence and echo planar imaging, and flow sensitive invention recovery (EPI-FAIR) MR sequence, and assess its value for clinical application in routine renal examination. Methods Forty volunteers (25 male and 15 female adults, aged 30 to 62 years) with normal renal function were included in this prospective study. All the subjects underwent 3.0 Tesla MR scanning using 3 MR scan modes, namely breath-holding EPI-FAIR, breath-holding SSFSE-FAIR and free breathing SSFSE-FAIR. Results SSFSE-FAIR without breath-holding was capable of differentiating the renal cortex and medulla with the corresponding rBFVs of 111.48 ± 9.23 and 94.98 ± 3.38, respectively. Breath-holding SSFSE-FAIR and EPI-FAIR failed to distinguish the borders of the renal cortex and medulla. The EPI-FAIR rBFV of mixed cortex and medulla value was 178.50±17.17 (95%CI:167.59, 189.41). Conclusion Breath-holding SSFSE-FAIR and EPI-FAIR can not distinguish the renal cortex and medulla due to a poor spatial resolution but can be used for rough evaluation of renal blood perfusion. Free breathing SSFSE-FAIR with an improved spatial resolution allows evaluation of the status of renal perfusion of the cortex and medulla.
Keywords:arterial spin labelingmagnetic resonance imagingkidney
Publication Date:2013-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:5( 1478-1482 )
Journal of Southern Medical University

Journal of Southern Medical University

PKUISTIC
ISSN:1673-4254
Year, Vol.(Issue):2013,(10)