Expression of nicotinic acetylcholine receptor mRNA in the marginal region of rat striatum
Abstract：Objective To study the distribution of nicotinic acetylcholinereceptor（nAChR） mRNA in the marginal region of rat striatum. Methods In situ hybridization of digoxin-labeled probes on sections of the rat brain was performed. Results Numerous nAChR-positive neurons were observed in the rat striatum. In the caudoputamen aggregated many multipolar positive neurons of moderate size and a number of fusiform positive neurons were present in the caudoputamen.There were some fusiform positive neurons in the marginal division,which were located in the marginal region between the caudate putamen and globus pallidus. Conclusion The neurons in the marginal region are capable of nAChR mRNA expression, suggesting that nAChR-positive neurons in the marginal region may exercise important functions in the process of learning and memory.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1-4 )