Preventive and therapeutic effect of acidic fibroblast growth factor on traumatic brain edema in rats
WANG Qing-hua
XU Ru-xiang
CAI Ying-qian
Zou Yu-xi
Abstract：Objective To observe the effect of acidic fibroblastic growth factor (aFGF) on traumatic brain edema. Methods Recombinant human aFGF (10mg/ml) was continuously injected into the intraventricle for 12 h before brain traumatic injury in rats, and the brain water content was determined and the histological and ultrastructural changes in the brain tissue observed. Results Brain edema and neuronal damage were reduced remarkably by the administration of aFGF. Conclusion aFGF can obviously alleviate brain edema and neuronal damage.
Keywords：brain traumaaFGFtreatment
Publication Date：2000-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 491-492 )