DOI: 10.1002/ame2.12563
Bird's eye view of natural products for the development of new anti-HIV agents:Understanding from a therapeutic viewpoint
Md.AI Amin
Mohamed H.Nafady
Mehrukh Zehravi
Sherouk Hussein Sweilam
Kusuma Praveen Kumar
M.Akiful Haque
Aziz Unnisa
Laliteshwar Pratap Singh
Mohammed Sayeed
Mohammed Ali Alshehri
Irfan Ahmad
Talha Bin Emran
Md.Zia Uddin
Abstract：Acquired immune deficiency syndrome (AIDS) is the name used to describe several potentially life-threatening infections and disorders that happen when HIV has severely compromised the immune system. The primary effect of HIV is to decrease host immunity, exposing the host to external pathogens. The development of pharmaceutical drugs that directly cure the infection is crucial because of the current wide-ranging epidemic of HIV. Most therapeutic anti-HIV drugs are nucleosides. However, their high toxicity and potential for drug resistance restrict their use. Many of the most effective clinical drugs used to inhibit HIV, the activation of latent HIV, and AIDS have been obtained from natural sources. This review focuses on potential natural medicinal products for treating and managing HIV and AIDS. Notwithstanding, further clinical research studies are needed to understand the subject and its dynamics.
Keywords：AIDSanti-HIV agentsHIVimmune systemmarine compoundsnatural productsphytoconstituents
Publication Date：2025-03-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：17( 441-457 )