Preliminary study on the efficacy of closed-loop repetitive transcranial magnetic stimulation combined with electroacupuncture in the treatment of neurogenic bladder after spinal cord injury
Zhou Fang
Xia Xiaomei
Lu Can
Zhu Xiuhua
Abstract：Objective To observe the therapeutic effect of closed-loop repetitive transcranial magnetic stimulation(rTMS)combined with electroacupuncture in patients with neurogenic bladder(NB)after spinal cord injury.Methods A total of 40 patients with neurogenic bladder after spinal cord injury who were admitted to the Department of Rehabilitation Medicine of The First People's Hospital of Lianyungang from March 2024 to June 2025 were selected and randomly divided into a control group and an observation group,with 20 patients in each group.The control group was given electroacupuncture treatment on the basis of conventional rehabilitation treatment,while the observation group was treated with closed-loop repetitive transcranial magnetic stimulation combined with electroacupuncture on the basis of conventional rehabilitation treatment.The treatment was conducted 5 times a week for a total of 8 weeks.Urodynamic indexes(maximum bladder capacity,detrusor pressure during urination,residual urine volume),voiding diary parameters(average daily catheterization frequency,urine volume per catheterization)and Neurogenic Bladder Symptom Score(NBSS)of the two groups were compared before and after 8 weeks of treatment.Results Intragroup comparison showed that after treatment,the maximum bladder capacity,detrusor pressure during urination,residual urine volume,urine volume per catheterization and NBSS score in both groups were improved compared with those before treatment(P<0.05).The average daily catheterization frequency in the observation group was improved compared with that before treatment(P<0.05),while no significant improvement was found in the average daily catheterization frequency in the control group(P>0.05).Intergroup comparison after treatment revealed that the urodynamic indexes,voiding diary parameters and NBSS score in the observation group were superior to those in the control group(P<0.05).Conclusion Closed-loop repetitive transcranial magnetic stimulation combined with electroacupuncture can improve the urodynamic indexes and urination function of NB patients after spinal cord injury,and can promote the recovery of bladder function.Its efficacy is better than that of electroacupuncture alone.
Keywords：Repetitive transcranial magnetic stimulationElectroacupunctureSpinal cord injuryNeurogenic bladder
Publication Date：2025-09-20
Online Publishing Date：2026-03-13(First online date of this platform, not the publication date of the document)
Pages：5( 59-63 )