Safety and efficacy of the Indigo large-lumen catheter in the treatment of high-and intermediate-risk pulmonary embolism:a single-center retrospective study
Fan Shixiang
Zhang Honggang
Li Da
Zhang Xiaosong
Wang Yusheng
Yuan Silong
Abstract：Objective To evaluate the safety and efficacy of the Indigo large-lumen catheter in the treatment of high-and intermediate-risk pulmonary embolism(PE).Methods A retrospective analysis was conducted on 65 patients with high-and intermediate-risk PE admitted to our center from October 2023 to April 2025.All patients underwent mechanical thrombectomy using the Indigo large-lumen catheter.Patient baseline characteristics,procedural parameters,safety and efficacy indicators,and follow-up outcomes were collected and analyzed.Results Compared with preoperative measurements,at 48 hours postoperation the right ventricle/left ventricle diameter ratio(RV/LV)decreased[(1.02±0.15)vs.(0.78±0.08),P<0.001],and the pulmonary artery systolic pressure decreased[(59.6±18.4)mmHg vs.(49.0±16.7)mmHg,P<0.001].The rate of major adverse events was 1.5％(1/65),consisting of one case of pulmonary hemorrhage.No all-cause mortality or symptomatic PE recurrence occurred during the 30-day follow-up period.Conclusion Mechanical thrombectomy using the Indigo large-lumen catheter is a safe and effective treatment for high-and intermediate-risk PE.It can significantly improve patients'physiological parameters,providing a new therapeutic option for PE.
Keywords：Pulmonary embolismMechanical thrombectomyIndigo Aspiration System
Publication Date：2025-08-20
Online Publishing Date：2026-01-30(First online date of this platform, not the publication date of the document)
Pages：6( 49-54 )