Expert consensus on diagnosis and treatment of coronary artery ectasia(reprinted)
Expert Group on Coronary Artery Ectasia,Professional Committee of Cardiovascular and CerebrovascularDisease Prevention and Management,China Association of Gerontology and Geriatrics
Zhao Huiqiang
Zhang Meng
Abstract：Coronary Artery Ectasia(CAE)is defined as a localized or diffuse dilation of the coronary artery lumen,with a diameter exceeding 1.5 times the adjacent normal vessel segment.The prevalence of CAE among patients undergoing coronary angiography ranges from 0.3%to 8.0%,and it is more commonly observed in middle-aged and older adults,males and smokers.The pathophysiological mechanisms of CAE are complex,involving inflammatory responses,increased matrix metalloproteinase activity,genetic factors,among others.Its clinical manifestations are diverse,ranging from asymptomatic cases to symptoms such as angina and myocardial infarction.Its diagnosis relies primarily on imaging techniques,including coronary angiography and computed tomography angiography.Given the complexity of CAE pathophysiology and its varied clinical presentations,the treatment strategies encompass pharmacological approaches(e.g.,antiplatelet anticoagulant,and lipid-lowering therapies),interventional procedures,and surgical treatments.However,the unified and standardized treatment protocols remain lacking.This expert consensus summarizes the current understanding of CAE,including its epidemiology,pathophysiology,clinical manifestations,diagnostic methods,and therapeutic strategies,to enhance CAE awareness,optimize diagnostic and treatment processes and improve the clinical outcomes.
Keywords：Coronary artery ectasiaPathophysiologyDiagnosisTreatmentPrognosis
Publication Date：2025-07-20
Online Publishing Date：2026-01-30(First online date of this platform, not the publication date of the document)
Pages：10( 19-28 )