Efficacy of oxiracetam in the treatment of hypertensive intracerebral haemorrhage patients
Ye Shengshou
Mo Zhixiao
Abstract：Objective To explore the clinical efficacy and safety of oxiracetam in the treatment of patients with hypertensive intracerebral hemorrhage.Methods A total of 100 patients with hypertensive intracerebral hemorrhage admitted from March 2023 to March 2025 were selected as the research subjects and divided into the observation group(n=50)and the control group(n=50)according to the random number table method.The control group was given conventional antihypertensive,dehydration,hemostasis and symptomatic supportive treatments.The observation group was additionally treated with oxiracetam on this basis.The clinical efficacy was compared between the two groups of patients,including the NIHSS score,GCS score,and ADL score before and after treatment,and the incidence of adverse reactions was recorded.Result The total effective rate of treatment in the observation group was 98.0%,and that in the control group was 86.0%.Through comparison,the treatment effect of the observation group was higher(χ2=4.891,P<0.05).The NIHSS score in the observation group decreased,while the GCS score and ADL score were higher than those in the control group(all P<0.05).The levels of IL-6,CRP and NSE in the observation group were all lower than those in the control group(all P<0.05).The incidences of adverse reactions in the two groups of patients were similar(χ2=0.210,P>0.05).Conclusion Oxiractam can significantly improve the neurological deficits and activities of daily living in patients with hypertensive intracerebral hemorrhage,reduce the levels of neurological injury markers,and has good safety.It is worthy of clinical promotion.
Keywords：OxiracetamHypertensive cerebral hemorrhageNeural function
Publication Date：2025-06-20
Online Publishing Date：2025-12-22(First online date of this platform, not the publication date of the document)
Pages：5( 56-60 )