Research progress in transcatheter arterial chemoembolization combined with targeting and immunotherapy for hepatocellular carcinoma
Zu Qingquan
Shi Haibin
Abstract：Hepatocellular carcinoma(HCC)is one of the most common malignant tumors worldwide.Most HCC patients are diagnosed at an advanced stage,losing the opportunity for radical surgical resection,resulting in an overall poor prognosis.In recent years,advancements in systemic therapy have reshaped the treatment landscape for HCC.Multidimensional and multimodal comprehensive treatment strategies have become the primary approach to overcome drug resistance and improve long-term outcomes in advanced HCC patients.Among these,interventional therapy not only can control local tumors but also plays a role in modulating the tumor microenvironment,synergizing with systemic therapies to enhance antitumor effects,thus making it a current research hotspot in HCC management.This article reviews the progress in studies combining transcatheter arterial chemoembolization(TACE)with targeted and immunotherapies,and discusses future directions and challenges in this field.
Keywords：Hepatocellular carcinomaImmunotherapyTranscatheter arterial chemoembolization
Publication Date：2024-10-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1-6 )