Impact of medication adherence on short-term efficacy in coronary heart disease patients and analysis of influencing factors

Zhang Shuo; Ding Fenghua; Chen Xin; Wu Hai; Chen Yixin; Wang Zhuoqing; Liu Xinyan; Ye Lingying

Abstract：Objective To explore the impact of medication adherence on the short-term efficacy of coronary heart disease(CHD)patients and to analyze the influencing factors of medication adherence.Methods Clinical data of 122 CHD patients admitted to our hospital were retrospectively analyzed.Based on the MMAS-8,patients were divided into an adherent group(77 cases)and a non-adherent group(45 cases).The efficacy of the two groups was compared,and univariate and multivariate analyses were performed to identify risk factors affecting medication adherence among CHD patients.Results The medication adherence rate among CHD patients was 63.11%(77/122).The efficacy of the adherent group was significantly better than that of the non-adherent group(P<0.01).Univariate analysis showed that factors affecting medication adherence included gender,marital status,cohabitation with children,and insurance status(P<0.05).Multivariate analysis using binary logistic regression revealed that marital status and cohabitation with children were independent influencing factors for medication adherence among CHD patients(P<0.01).Conclusion The short-term efficacy of CHD patients is closely related to medication adherence.Good adherence helps improve clinical efficacy.Medication adherence among CHD patients is influenced by marital status and whether they live with their children.Future efforts should focus on managing these influencing factors to improve medication adherence.