The Diagnostic Value of DCE-MRI Combined with DWI in Different Pathological Types of Uterine Fibroids
CHEN Yuexi
CHEN Wenhui
LIU Ning
MA Liang
YE Meiyan
Abstract：Objective:The aim of this study was to investigate the diagnostic utility of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with DWI in differentiating various pathological types of uterine fibroids.Method:Fifty MRI scans were retrospectively acquired in patients with uterine fibroids,including both DCE-MRI and DWI scans.In cases of multiple fibroids,the one with the largest volume was selected for analysis.Fibroids were confirmed in all patients using postoperative pathology,and were categorized into common(27 cases),rich-cell(6 cases),and degenerative(17 cases)types.The diagnostic performance of DCE-MRI,DWI,and their combination across different pathological types was assessed.Results:MRI accurately localized the fibroids,identifying 15 subserosal,27 intramural,and 8 submucosal fibroids.In DWI,rich-cell-type fibroids exhibited significantly higher signal intensity and lower Apparent diffusion coefficient(ADC)values compared to normal and degenerative types;In DCE-MRI,the quantitative parameters Ktrans and Kep were significantly higher in rich-cell-type fibroids than the normal and degenerative types.The combined examination demonstrated significantly higher diagnostic sensitivity compared to individual DCE-MRI or DWI.Conclusion:The application of DCE-MRI combined with DWI showed significant clinical value in the differential diagnosis of uterine fibroids of various pathological types.
Keywords：magnetic resonance diffusion-weighted imagingdynamic contrast-enhanced magnetic resonance imaginguterus fibroidspathological types
Publication Date：2025-05-31
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 455-460 )