3D CT Value Analysis of Ground Glass Shadow and Coelentereous Growth in Stage ⅠInvasive Lung Adenocarcinoma

LIU Li-wei; ZHANG Long-jiang; QIAN Bin

doi:10.15953/j.1004-4140.2018.27.01.15

Abstract：Objective: To investigate the relationship between ground glass opacity and the pathologic climax-like growth in patients with stage I invasive lung adenocarcinoma by three-dimensional CT. Methods: A total of 168 patients with stage Ⅰ invasive pulmonary adenocarcinoma who were treated from June 2013 to June 2017 were selected. The components of ground glass in stage Ⅰ invasive lung adenocarcinoma were calculated by three-dimensional CT quantitative analysis software and the largest radial line measurement ratio, semi-quantitative assessment of the invasive growth of the adherent adenocarcinoma composition, and the correlation between the two. Results: The proportion of ground glass components was (0.21 ±0.18), the percentage of ground glass components was (0.44 ±0.36), the semi-quantitative analysis of pathological sections the ratio was (0.29 ±0.24). There was a positive correlation between the proportion of ground glass components and the proportion of climax-like growth components (r = 0.634 and 0.598, P = 0.000) by three-dimensional CT quantitative analysis and maximum diameter line analysis. The ratio of ground glass to the ratio of ground-glass components measured by the maximum diameter method was 3.8％. Outside the 95％ confidence interval, the three-dimensional CT value was 4.4％. There was no significant difference between the two methods (P > 0.05). Conclusion: The three-dimensional quantitative analysis of stage I invasive lung adenocarcinoma patients with ground-glass components and climax-like growth component has a significant correlation, which has a significant clinical significance in the diagnosis of secondary pathology, and compared to the maximum diameter method is more comprehensive reflect the stage I invasive lung adenocarcinoma of the tumor status.