The Study of the Image Quality of Dual Energy Spectral CT in the Assessment of Myocardial Infarction

BU Yu-lian; ZHANG Huan; PAN Zi-lai; YANG Wen-jie; CHEN Ke-min; YAN Fu-hua

doi:10.15953/j.1004-4140.2016.25.03.04

Abstract：Objective: To study the effectiveness of the functional parameters of spectral CT, and to explore their clinic values of image quality in the evaluation of myocardial infarction (MI), so as to provide a novel and reliable imaging diagnostic system for early detection of MI. Methods: 30 patients with coronary heart disease were scanned with the conventional coronary CT angiography (CCTA) and the dual energy spectral imaging modes. In addition, all cases had the Cardiac MRI scan within a week. CCTA images were used to measure stenoses. The optimal contrast-to-noise ratio (CNR) and the optimal monochromatic energy levels for displaying infractions were measured from 1 min and 3 min monochromatic images. Record the image noise according to the optimal monochromatic energy levels. The results were compared with those measured from conventional 140kVp polychromatic images. Detect MI in MRI perfusion images and compare with those detected by CT. Results: Spectral CT have detected 36 regions of MI and had good correlation with the myocardial perfusion images of MRI (r=100%,P=0.00). All spectral CT-identified MI had associated coronary artery with more than 50% stenosis of the intravascular diameter (71.7%±16.2%). The optimal CNR for displaying infractions of 1 min and 3 min monochromatic images were significant higher than the CNR of conventional 140kVp polychromatic images (P<0.05). The image noise according to the optimal monochromatic energy levels of 1 min and 3 min monochromatic images were significant lower than conventional 140kVp polychromatic images (P<0.05). Conclusions: The GSI mode of dual energy spectral CT greatly improves the image quality and the efficiency of the detection of MI.