Diagnostic Value of 18F-FDG PET/CT for Gynecological Malignancies

Abstract：Objective：To investigate the diagnostic value of 18 F-FDG PET/CT in pre-operative diagnosis and post-operative follow-up of gynecological malignancies.Materials and Methods：33 patients（17 patients who were doubted malignant tumors and 16 patients who were suspected recurrence or metastasis after operation）were scanned by 18 F-FDG PET/CT.The results were compared with the conventional imaging modalities.Results：In 17 patients who were doubted malignant tumors,the patients-based diagnostic ability of PET/CT was similar with conventional imaging modalities.For metastasis diagnosis,the sensibility,specificity,accuracy,positive predictive value and negative predictive value of the two methods were 85.7%vs 28.6%,100%vs 100%,94.1%vs 70.6%, 100%vs 100%,90.9%vs 66.7%.The sensibility of the two methods had significant difference.And the lesion-based accuracy of PET/CT for metastasis was also significantly higher.In 16 patients who were suspected recurrence or metastasis after operation,The lesion-based sensibility,specificity,accuracy,positive predictive value and negative predictive value of the two methods were 76.9%vs 48.7%,77.8%vs 66.7%,77.1%vs 52.1%, 93.8%vs 86.4%,43.8%vs 23.1%.The sensibility and accuracy of PET/CT were higher than that of conventional imaging modalities significantly.Conclusion： 18 F-FDG PET/CT,as a non-invasive imaging modality,has considerable value in pre-operative diagnosis and post-operative follow-up of of gynecological malignancies.