Gamma stereotactic radiotherapy for early primary liver cancer
SHAO Liang
KONG Xin
SHI Yan-xin
MA Ming
ZHANG Ping
NIU Ting-ting
LI Chun-tian
Abstract：Objective To explore the clinical effect of gamma stereotactic radiotherapy for early primary liver cancer. Meth-ods A retrospective study was performed on 45 patients with early primary liver cancer who were admitted from June 2011 to June 2014. Patients were performed gamma knife therapy,treatment plan were according to the size,position of lesions to perform single target of multiple target radiotherapy;the single dose,sub total dose and time division were according to size, position of lesions, whole body status, surrounding tissue radiation sensitivity. After 3 months of radiotherapy, short-term effect were evaluated,to observe the life quality changing status,lesions remission rate and adverse reactions. Results After treatment for 3 months reviewing abdominal enhanced CT,there were 12 cases(26. 66%) of completely relieved,27 cases (60. 00%) of partial relieved,and the total effective rate was 86. 66%. A fetoprotein(AFP) all showed varying degrees of decline,31 cases with the AFP less than 20 μg/L. Among 32 cases of liver area pain,23 cases of complete resolution of symptoms,and 6 cases reduced. Check after half an year,local progression-free survival rate was 78%,1 year local progres-sion-free survival rate was 31%,and 2 years after partial progression-free survival rate was 15%. No serious adverse reac-tions such as radiation hepatitis or gastrointestinal bleeding. Conclusion The gamma knife radiotherapy for primary liver cancer is safe and effective,with less or mild adverse reaction,wich is worth clinical promotion.
Keywords：Liver cancerGamma knifeRadiotherapy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 36-37,53 )