Effects of extracorporeal membrane oxygenation on acute lung injury induced by se-vere trauma
LIU Yun-en
TONG Chang-ci
CONG Pei-fang
ZHANG Yu-biao
SHI Lin
LIU Ying
LIU Xue-lei
JIN Hong-xu
GAO Yan
HOU Ming-xiao
Abstract：Objective To investigate the effects of extracorporeal membrane oxygenation on acute lung injury induced by severe trauma in dogs. Methods Twenty beagle dogs were randomly divided into 4 groups,normal control group( Group A) ,model group( Group B) ,mechanical ventilation treatment group( Group C) ,and ECMO treatment group( Group D) . The differences of vital sign,hemodynamics,blood gas analysis and routine blood test were compared between different groups. Results The rate of heart and respiration in Group D was lower than those in Group C(P<0. 05). In Group D,value of mean arterial pressure,right atrial pressure and right ventricular pressure was better than those in Group C(P<0. 05). Comparing with the value in Group C,the value of PaCO2 and PaO2 in Group D was better. The number of red cell and white cell,and the content of hemoglobin of routine blood test in Group D was better than those in Group C(P<0. 05). Conclu-sion Extracorporeal membrane oxygenation has a good effect on severe trauma induced acute lung injury.
Keywords：Extracorporeal membrane oxygenationAcute lung injuryMechanical ventilationImpact trauma
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1-5 )