Recent advances in complications of snakebiteenvenomation:pathogenesis and treatment strategies
Yang Cui
Li Shasha
Deng Fangfang
Yang Guangli
Yan Tiantian
Zhang Tianxi
Abstract：Snakebite envenomation(SBE)represents a prevalent and potentially fatal clinical emergency,frequently accompanied by both localized and systemic complications,including coagulopathy,compartment syn-drome,renal failure,and neurological damage.In severe instances,multi-organ failure may ensue,posing a signifi-cant threat to patient survival.Though timely administration of antivenom has proven effective in preventing SBE-re-lated complications,its utilization is constrained by the issues of accessibility,affordability,and species specificity.Furthermore,the inadequate early recognition of complications and insufficient follow-up treatment in clinical settings have contributed to the persistent occurrence of long-term sequelae following SBE incidents.This comprehensive re-view aims to delineate recent progress in the study of SBE-associated complications,including their pathogenesis,clinical manifestations,diagnostic and therapeutic strategies,and rehabilitation approaches,with the ultimate objec-tive of enhancing clinical management,diagnostic and treatment approaches,and rehabilitation strategies for SBE complications.
Keywords：Snakebite envenomationComplicationsManagement strategiesTherapeutic advances
Publication Date：2026-01-15
Online Publishing Date：2026-03-03(First online date of this platform, not the publication date of the document)
Pages：7( 71-77 )