Nanozymes in the treatment of traumatic brain injuries:recent advances
Hong Xinjie
Xu Tao
Hou Lijun
Abstract：Traumatic brain injury(TBI)has a high mortality and disability rate,with the mechanism of ex-cessive production of reactive oxygen species(ROS)in the early stage leading to secondary damage being particular-ly critical.Nanozymes,as a novel nanomaterial with enzymatic properties,have attracted wide attention due to their ability to selectively scavenge ROS.Compared to natural enzymes,nanozymes show significant advantages in catalyt-ic activity,cost-effectiveness,stability,and ease of storage.This review discusses the research progress of nanozymes in TBI treatment,systematically introduces the application research of organic nanozymes,cerium-based nanozymes,and single-atom nanozymes,and proposes a prospect for future development directions of nanozymes.
Keywords：Brain injuriestraumaticNanozymesReactive oxygen speciesResearch progress
Publication Date：2025-06-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 472-475 )