Incidence of delirium and influencing factors in patients with mild traumatic brain injuries
Li Jiayu
Liu Suyun
Mo Jingshu
Li Haijuan
Xu Guangyuan
Zhou Xiaozhou
Zhang Yingying
Shen Yin
Abstract：Objective To investigate the incidence and risk factors of delirium in patients with mild trau-matic brain injuries(mTBI).Methods A total of 107 patients admitted to the Department of Emergency Medicine of the People's Hospital of Guangxi Zhuang Autonomous Region from Jan.2021 to Dec.2023 and diagnosed as mT-BI according to the Guidelines for Clinical Treatment of Craniocerebral Trauma were prospectively included.The in-cidence of delirium was evaluated by using the Chinese Revised Version of Confusion Assessment Method(CAM-CR)every 24 h within 72 h after admission.At the same time,clinical indicators such as age,gender,comorbidity,serum potassium,sodium,creatinine,and albumin on admission,and Pittsburgh Sleep Quality Index(PSQI)at 24 h after admission were collected.The patients were divided into delirium group and non-delirium group according to whether delirium occurred or not.The relevant clinical indicators of the two groups were compared,and the risk fac-tors of delirium were screened by univariate analysis and multivariate Logistic regression analysis.Results Of the 107 mTBI patients,delirium occurred in 41 during hospitalization,with an incidence of 38.32％(95％CI:22％-47.7％).The delirium group revealed much higher age,proportions of patients with coronary heart disease or hyper-tension,PSQI at 24 h after admission,and WBC and CRP levels,while much lower levels of serum sodium,potassium and albumin,revealing significant differences when compared with the non-delirium group(all P＜0.05).Logistic multivariate analysis further showed that age(OR=1.208,95％CI:1.089-1.341),serum sodium(OR=0.758,95％CI:0.624-0.920),serum albumin(OR=0.755,95％CI:0.586～0.971),and PSQI index at 24 h after admission(OR=2.725,95％CI:1.237-6.002)were independent risk factors for the incidence of delirium in mTBI patients during hospitalization(all P＜0.05).Conclusion The increase of age and PSQI were significantly associated with the increased risk of delirium incidence during hospitalization of mTBI patients,while the increase of serum sodium and albumin levels was associated with decreased risk.
Keywords：Brain injuriestraumaticDeliriumRisk factors
Publication Date：2024-07-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 512-516 )