Application of bone cement prosthesis in elderly patients undergoing THA surgery and analysis of coagulation function
ZHAN Peng
ZHAO Chang
ZHANG Yu
Abstract：Objective To investigate the effect of bone cement prosthesis on the changes of blood coagula -tion function in elderly patients undergoing total hip replacement(THA).Methods Data of 256 elderly patients in our hospital for surgical treatment of THA(Jan.2014 to Dec.2016)were analyzed retrospectively,including 128 patients with bone cement prosthesis(group A),and 128 patients with cementless prosthesis(group B).Operation index,postoperative hip function index and blood coagulation index were compared between the two groups.Results The operation time of group A was(130.6 ±19.4)minutes,longer than that of group B(103.2 ±15.8)minutes (P<0.05).There was no significant difference in intraoperative blood loss and length of stay between group A and group B(P>0.05).At 1 month,3 months,and 6 months after surgery,Harris functional scores in group A was (45.2 ±11.6),(71.8 ±9.2),(83.1 ±7.4)points,respectively,and in group B was(47.0 ±13.4),(73.0 ± 10.8)and(84.8 ±9.5)points,respectively,without significant difference between the two groups(P>0.05).The Harris functional scores showed a significant increase trend at 1 month after surgery,3 months after operation,and 6 months after operation.Preoperatively,there was no significant difference in PTA,APTT,Fib,R,k,and alpha angles between group A and group B(P>0.05).At 30 minutes after implantation,the PTA(82.9 ±4.7)%,Fib(3.59 ±0.31)g/L,and αangle(73.0 ±12.1)°were significantly higher in group A than in group B(79.4 ±4.4)%,Fib (3.10 ±0.28)g/L,α(67.2 ±11.6)°(P<0.05).The APTT(33.3 ±3.9)s,R value(4.04 ±0.69)min,and k value(1.47 ±0.09)min in group A were less than the APTT(36.8 ±4.1)s,R value(4.98 ±0.87)and k value (1.61+0.12)min in group B(P<0.05);at 3 h after surgery,there was no statistical difference in PTA,APTT, Fib,R,k,and αangle groups between group A and group B(P>0.05).There was no significant difference in the rate of surgical complications between the two groups(P>0.05).Conclusion There is no difference in hip func-tion and cementless prosthesis after cement implantation in elderly patients with THA surgery.However,the risk of hypercoagulability increases within 3 hours after implantation of cemented prosthesis.Close monitoring is required for coagulation function changes.
Keywords：total hip replacementbone cement prosthesiscoagulation functionelderly
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 353-357 )