Increased serum Procalcitonin levels as an index of antibiotics usage in snake-bite patients
LUO Jie
HUANG Jian
Abstract：Objective To investigate the role of increased serum Procalcitonin(PCT)levels on treatment of snake-bite patients with antibiotics.Methods Totally 414 snake-bite patients admitted in Chongqing Emergen-cy Medical Center from Jan.2015 to Dec.2015 were retrospectively analyzed.Totally 197 patients(group A,124 males and 73 females with an average age of 42.12 years)used antibiotics under the instruction of common indicators such as white blood cell count,C-reactive protein(CRP)and body temperature,while the other 217 cases(group B, 152 males and 65 females with an average age of 44.43 years)used antibiotics under the guidance of increased serum Procalcitonin levels.The hospitalized days,the antibiotic usage rate,the antibiotic usage days,hospitalization costs,the rates of the abscess,tissue necrosis,and sepsis were observed between the two groups.Results Compared to group A,the hospitalized days((5.74 ±1.94)d vs.(6.32 ±2.77)d;P<0.05),the antibiotic usage rate(51.61% vs. 67.01%,P<0.05),the antibiotic usage days((4.14 ±1.01)d vs.(4.55 ±1.65)d;P<0.05)and hospitalization costs((4192.18 ±2119.68)yuan vs.(4755.23 ±2579.31)yuan;P<0.05)were significantly decreased in group B.The rates of the abscess,tissue necrosis,and sepsis had no statistical difference between the two groups(P>0.05).Conclusion Procalcitonin can be used as an indicator to guide the use of antimicrobial drugs for snake bites patients,which can effectively control infection,and reduce the usage of antibacterial drugs.
Keywords：snake-biteprocalcitonionantibiotic
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 146-148 )