Clinical significance of monitoring BMO2 UC and arteriovenous blood lactate difference in patients with severe craniocerebral injury
ZHANG Cheng-jun
CHEN Xiao-yan
LUO Song
FU Yu
Abstract：Objective To explore the application value of brain meliorate oxygen utilization rate ( BMO2 UC) and arteriovenous blood lactate difference in severe craniocerebral injury .Methods Retrospective a-nalysis was carried out in 94 patients with craniocerebral injury treated in Yuechi People 's Hospital of Guang 'an from Mar.2014 to Jun.2016.Among them were 35 patients with severe craniocerebral injury (severe group), and 59 patients with mild and moderate craniocerebral injury ( mild and medium group ) .There were 24 males and 11 fe-males in the severe group , with an average age of 38.91 years.Causes of injury included road traffic injuries in 22 cases and falling injury in 13 cases.Types of brain injury included subdural hematoma in 5 cases, multiple hemato-ma in 9 cases, intracerebral hematoma in 10 cases, herniation in 7 cases and skull base fracture in 4 cases.In the mild and medium group, there were 39 males and 20 females, with an average age of 39.02 years.Causes of injury included 31 cases of road traffic injuries and 28 cases of falling injuries .Types of brain injury included subdural he-matoma in 10 cases, multiple hematoma in 12 cases, intracerebral hematoma in 21 cases, herniation in 9 cases, and skull base fracture in 7 cases.The levels of BMO2UC and VALa were measured by automatic blood gas analy-zer.The correlation between BMO 2 UC and VALa levels and admission GCS score and mortality was analyzed .Re-sults The BMO2 UC and VALa in the severe group were (0.21+0.07)%and (-0.18+0.08) mmol/L, which were significantly lower than those in the mild and medium group ( P<0.05 ) .The GCS score of 94 patients was (8.10+2.63) at admission, and the Pearson correlation analysis showed that the GCS score at admission was nega-tively correlated with BMO2UC and VALa (r=-0.655 and -0.511, P<0.05).Of the 94 patients, 26 cases died and the fatality rate was 27.66%.The BMO2 UC and VALa of the dead patients were (0.15+0.06)% and (-0.11+0.07 ) mmol/L, significantly lower than those of the survived patients ( P <0.05 ) . Conclusion BMO2 UC and VALa in patients with severe traumatic brain injury were significantly decreased .BMO2 UC and VALa could reflect the degree of brain injury in a certain extent , and had certain value in evaluating the prognosis of pa-tients.
Keywords：brain injurybrain meliorate oxygenutilization ratearteriovenousblood lactic acid
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 929-931 )