Efficacy of negative pressure drainage combined with alginate dressing in refractory burn wound

YANG Jiang-yan

doi:10.3969/j.issn.1009-4237.2016.12.013

Abstract：Objective To evaluate the efficacy of negative pressure drainage combined with alginate dress-ing in refractory burn wound .Methods One hundred patients with refractory burn wound were divided into the ob-servation group(n=50) and the control group(n=50).The control group was treated with negative pressure drain-age combined with medical sponge material .The observation group was treated with negative pressure drainage com-bined with alginate dressing .The bacteria culture positive rate of wound secreta , dressing changing times , wound healing time,fresh granulation growth time and clinical efficacy were compared between the two groups .Results At 1d,7d and 14d after treatment,the bacteria culture positive rates of wound secreta in the observation group was 92.0%(46/50),26.0%(13/50) and 2.0%(1/50),respectively;while those of the control group was 90.0%(45/50),48.0%(24/50) and 14.0%(7/50),respectively.At 1d after treatment,the bacteria culture positive rates of wound secreta in the two groups were not statistically different (P>0.05).At 7d and 14d,the bacteria cul-ture positive rates of wound secreta in the observation group were significantly less than those of the control group (P<0.05).The dressing changing times,wound sealing time and fresh granulation growth time of the observation group was (5.1 ±1.2)times,(28.2 ±4.3)d and(15.4 ±2.7)d,respectively ;while those of the control group was (7.2 ±1.5)times,(35.1 ±3.8)d and(22.3 ±3.5)d,respectively,and the differences were statistically significant (P<0.05).The clinical efficacy of the observation group and the control group was 92.0%(46/50) and 64.0%(32/50),respectively,and the differences were statistically significant (P<0.05).Conclusion Negative pressure drainage combined with alginate dressing in refractory burn wound can obviously reduce the wound bacterial infection and promote the fresh granulation tissue growth and wound healing .