Observation of the effect of preemptive analgesia on patients with anterolateral thigh flap
BAI Yan
LI Xia
DU Di
XU Xiao-yan
WU Yi-peng
Abstract：Objective To observe the effect of preemptive analgesia on the anterolateral thigh flap in pa-tients undergoing analgesia.Methods Totally 120 patients[85 males and 35 females ranged from 35-55 (average, 44.05) years] undergoing femoral anterolateral thigh perforator flap transplantation were divided into group A (60 cases) and group B(60 cases).Among them 38 were injured from heavy objects,47 from traffic accidents,24 from machines,5 from knives,4 from electrical injury,1 from scald and 1 from snake bites.Patients in group A were managed with 40mg intramuscular injection of parecoxib sodium for preemptive analgesia at 30 min before opera-tions,and patients in group B were not injected parecoxib sodium .Results All patients received 1 months of fol-low-up,and all the flaps survived.After 24 h of operation,the number of cases in group A in use of analgesic drugs (diclofenac sodium) was smaller than that of group B(P<0.05).After 6h,12h,24h,the NRS score of group A was lower than that of group B (P<0.05),while there was no significant difference at 48h after operations between the two groups ( P>0.05 ) . The number of cases of vascular crisis occurred in group A was smaller than that of group B(P<0.05).Conclusion The application of preemptive analgesia in patients with anterolateral thigh flap transplantation significantly reduced postoperative pain and the incidence of postoperative vascular crisis ,increasing patients’postoperative satisfaction .
Keywords：preemptive analgesiaflapanterolateral thigh
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 469-471 )