Clinical analysis on the effect of low molecular weight heparin and intermittent pneumatic compression against deep venous thrombosis following traumatic brain injury
DENG Yong-bing
XIAO Hong
HU Xi
LIU Ke
Abstract：Objective To explore the efficacy and safety of low molecular -weight heparin ( LMWH) and intermittent pneumatic compression ( IPC) against deep venous thrombosis ( DVT) following traumatic brain injury (TBI).Methods The clinical data of 682 patients with TBI from Mar.2010 to Mar.2013 were analyzed retro-spectively.In those cases,148 cases received LMWH injection,173 cases received IPC prevention,169 cases re-ceived LMWH and IPC ,192 cases did not receive LMWH or IPC prevention .DVT was diagnosed by color duplex ultrasonography or computed tomo-venography(CTV).Results There were 19 cases of DVT (12.83%),23 cases of DVT (13.29%),14 cases of DVT (8.28%) and 38 cases of DVT (19.80%) in the group of LMWH preven-tion,group of IPC prevention,group of LMWH+IPC prevention and group of non-preventive measure,respectively. The incidence of DVT in group 1,2 and 3 was significantly lower than that in group 4 (P<0.05).The incidence of DVT in group 3 was significantly lower than that in group 1 or 2(P<0.05).Conclusion LMWH and IPC are ef-fective in preventing DVT following TBI .Meanwhile ,application of LMWH in combined with IPC can achieve better efficacy.
Keywords：brain injuryvenous thrombosislow molecular-weight heparinpneumatic compression
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 430-433 )