Experiment study on infection of gunshot wound in hypothermia environment
Abstract：Objective To investigate the development process and characteristics of the infection after gunshot hypothermia environment.Methods The model of gunshot wound at hind limb of dogs in hypothermia environment was established.The level of bacteria in wound tissue and LPS level in plasma were tested.Results The levels of bacteria in wound tissue were increased to 104cfu/g,106cfu/g and 107cfu/g respectively at 8,48 and 96h after injury.No significant increase of LPS amount in plasma was observed and the close correlated relationship between changes of level of bacteria in wound tissue and LPS level in plasma were found(r=0.7596).Conclusion The results suggest that the hypothermia shows the strong effect to change of bacteria level in tissue of gunshot wound,both the speed of infection development and serious extent of infection of gunshot wound in hypothermia environment were lower than those in regular temperature.It is important to consider the effect of hypothermia on infection in the management of gunshot wound and trauma.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 119-121 )