Prevalence and treatment analysis of Helicobacter pylori infection in Suixi area,Anhui Province
Li Tao
Zhou Bing
Wang Hui
Zhang Zhennan
Zhang Keke
Abstract：Objective To analyze the prevalence,risk factors and the outcomes of standardized treatment for Helicobacter pylori(Hp)infection in the Suixi area of Anhui Province,thereby providing a theoretical basis for improving gastrointestinal health and reducing the risk of gastric cancer and other related diseases among local residents.Methods A total of 13 188 patients who underwent 14C-urea or 13C-urea breath tests as outpatients or inpatients at the Affiliated Hospital of Huaibei Vocational and Technical College between July 2023 and March 2025 were included.Data on Hp infection rates,demographic characteristics,risk factors,and treatment outcomes were analyzed using SPSS 26.0.Strict quality control measures,including instrument calibration and standardized procedures,were implemented prior to testing to ensure the accuracy of the results.Results Among the 13 188 patients included in the analysis,7 736 were Hp-positive,yielding an infection rate of 58.63%.The infection rate in rural areas(58.10%)was significantly higher than that in urban areas(41.90%)(P<0.001).Multivariate analysis identified male gender(OR=1.234),age≥50 years(OR=2.156),communal dining habits(OR=1.345),and a family history of Hp infection(OR=2.567)as independent risk factors for Hp infection(P<0.001).The standardized treatment rate(with a 14-day bismuth-containing quadruple therapy)was 82.30%(6 365/7 736),and the effective treatment rate(successful eradication)was 78.59%(5 002/6 365).The primary reasons for treatment failure included clarithromycin resistance(15.20%),metronidazole resistance(12.30%),and poor patient compliance(72.50%).Conclusion The Hp infection rate in Suixi area of Anhui Province is relatively high,demonstrating an epidemiological profile characterized by a higher prevalence in rural than urban areas than in urban settings and significant household clustering.Although the standardized treatment rate is satisfactory,the effective treatment rate is substantially compromised by antibiotic resistance and poor patient adherence.It is recommended to mitigate the Hp infection burden in this region through enhanced public health education,targeted family screening,and the optimization of personalized treatment regimens.
Keywords：helicobacter pyloriinfection prevalencerisk factorstreatment analysisSuixi area
Publication Date：2025-12-30
Online Publishing Date：2025-12-30(First online date of this platform, not the publication date of the document)
Pages：6( 577-581,586 )