Analysis of MRI features of hepatic epithelioid hemangioendothelioma
LIU Na
FAN Wenping
LIU Jia
LI Shuo
ZHANG Jianzeng
GAO Yinjie
GAO Xudong
XU Wenjuan
Abstract：Objective To explore the magnetic resonance imaging(MRI)features of hepatic epithelioid hemangioendothelioma(HEHE).Methods A retrospective analysis was conducted on the MRI data of 15 treatment-naïve patients with pathologically confirmed HEHE.These patients were from the Fifth Medical Center of the PLA General Hospital and the outpatient department dispatched by the Xinjiang Military Region General Hospital from October 2011 to January 2025.The MRI characteristics of the lesions were evaluated.Results A total of 157 lesions were identified among the 15 patients.Fusion of lesions was observed in 12 cases,and hepatic capsular retraction was present in 4 patients(26.67%).Lung metastases occurred in 4 patients(26.67%).MRI revealed a multi-layer ring appearance,which was most clearly demonstrated on T2-weighted images(T2WI)and delayed-phase images.Two-and three-layer structures were the most common,while a four-layer structure was observed in only one patient.On diffusion-weighted imaging(DWI),all lesions exhibited a double-layer appearance:hyperintense in the peripheral and slightly hyperintense in the center.Blood vessel penetration was observed in most lesions,including 133(84.71%)portal vein branches,15(9.55%)hepatic vein branches,and 6(3.82%)hepatic artery branches.Notably,all four patients with hepatic vein branch penetration developed lung metastases.Conclusion The multi-layer ring appearance and vascular penetration sign are two characteristic MRI features of HEHE,which may have significant implications for the clinical diagnosis and treatment.
Keywords：hepatic epithelioid hemangioendotheliomamulti-layer ring appearancevascular penetration signimaging features
Publication Date：2025-12-30
Online Publishing Date：2025-12-30(First online date of this platform, not the publication date of the document)
Pages：7( 544-549,556 )