Influence of family environmental factors on the occurrence of recurrent respiratory tract infections occurred in moderate-to-late preterm infants from birth to 3 years of age
FU Linlin
YANG Qing
YANG Hongli
ZHANG Ximeng
ZHANG Yang
GAO Han
ZHANG Hongjuan
MA Yanna
Abstract：Objective Exploring the impact of family environmental factors on the incidence of recurrent respiratory tract infections(RRTIs)in moderate-to-late preterm infants from birth to 3 years of age,analyzing the intrinsic mechanisms underlying preterm infants as a high-risk population for RRTIs,and providing targeted intervention strategies for respiratory infection prevention in preterm infants based on the universal characteristics of household environmental risk factors.Methods A prospective cohort study design was adopted,enrolling 386 moderate-to-late preterm infants born at our hospital from January 2019 to January April 2022,who were followed up until 3 years of age.According to the occurrence of RRTIs,the children were divided into an occurrence group and a non-occurrence group.Comprehensive clinical data were collected,covering multiple dimensions such as family living environment,demographic characteristics,and nutritional status.Logistic regression was used to analyze the influencing factors of RRTIs within 3 years of age in moderate-to-late preterm infants.Results Among 386 moderate-to-late preterm infants,184(47.67%)developed RRTIs.There were statistically significant differences between the 2 groups in living environment,multi-child family,household registration type,parents'education level,family nutritional conditions,parental allergic constitution,pet keeping,APGAR score,and history of illness(P<0.05).Logistic regression analysis showed that poor living environment,multi-child family,rural household registration,low parental education level,poor family nutritional conditions,parental allergic constitution,pet keeping,low APGAR score,and history of disease were influencing factors for RRTIs in moderate-to-late preterm infants within 3 years of age(OR>1,P<0.05).Conclusion Poor living environment,multi-child family,rural household registration,low parental education level,poor family nutritional conditions,parental allergic constitution,pet keeping,low APGAR score,and previous diseases significantly increase the risk of RRTIs in moderate-to-late preterm infants within 3 years of age.Early diagnosis and treatment can be developed based on these risk factors may help reduce the occurrence of RRTIs.
Keywords：moderate-to-late preterm infantswithin 3 years of agerecurrent respiratory tract infectionsenvironmental factors
Publication Date：2025-10-30
Online Publishing Date：2025-11-19(First online date of this platform, not the publication date of the document)
Pages：7( 478-483,490 )