Research progress on the role of regulatory T cells in acute respiratory infections
WU Meirong
Abstract：Acute respiratory infections pose a serious global public health challenge.While inflammation induced by infection helps eliminate pathogens,excessive inflammatory responses can lead to tissue damage and worsening of the diseases.CD4+FOXP3+regulatory T cells(Tregs)play a pivotal role in limiting acute lung inflammation and tissue damage by suppressing overactivation of the innate and adaptive immune systems.Additionally,Tregs contribute to lung tissue repair and promote the restoration of pulmonary function.This article reviews the roles of Tregs in acute respiratory infections and their underlying mechanisms,focusing on their mechanisms in inflammation resolution and tissue repair.Furthermore,it explores potential therapeutic strategies targeting Tregs,aiming to provide insights for clinical treatment.
Keywords：regulatory T cellsinflammatory responseacute respiratory infections
Publication Date：2025-08-30
Online Publishing Date：2025-08-28(First online date of this platform, not the publication date of the document)
Pages：5( 408-412 )