Research Progress on B7 Family Molecules in Viral Infections
LI Yi
ZHENG Xuyang
ZHANG Ying
Abstract：Viral infections are often accompanied by immune dysfunction,resulting in either hyperimmunity or immune tolerance,triggering series of pathological damages.The initiation of adaptive immune response requires not only MHC molecules to present processed antigens but also a class of co-stimulatory molecules serve as a"second signal".The B7 family is a group of co-stimulatory molecules that can bind to lymphocyte surface receptors and determine the activation or inhibition of immune response.These moleculesare crucial for immune regulation.This review summarizes the recent research progress on the role of B7 family co-stimulatory molecules in viral infections,aiming to provide insights for future mechanism and application research.
Keywords：co-stimulatory moleculesB7 familyviral infectionadaptive immune response
Publication Date：2025-06-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 301-306 )