Meta-analysis of influencing factors of multi drug resistant bacteria infection in intensive care unit
XIE Mingxia
LU Yueqin
PU Zunguo
Abstract：Objective To systematically evaluate the factors affecting infection with multi-drug resistant organisms (MDRO) in an intensive care unit (ICU). Methods Case-control or cohort studies on MDRO infection in ICU patients were retrieved from Ovid,PubMed,CNKI,Embase,WanFang,and other major databases with the retrieval time from July 2024. After screening the literature,evaluating it,and extracting valid data,statistical analysis was performed using RevMan5.3 software. Results A total of 11933 ICU patients were included in 23 studies. The results of meta-analysis showed that ICU days MD=5.05,z=5.710,P=0.000. Days of hospitalization MD=12.62,z=9.160,P=0.000. Acute physiological and chronic health evaluation (APACHE) score MD=1.78,z=5.820,P=0.000. Surgery OR=1.390,z=1.410,P=0.16. Intravenous catheterization OR=3.600,z=4.570,P=0.000. Combination of antibiotics OR=5.540,z=15.330,P=0.000. Conclusion ICU days,length of stay,APACHE score,intravenous catheterization,and combination of antibiotics are the factors influencing MDRO infection in ICU patients,and these should be paid clinical attention to.
Keywords：intensive care unitinfluencing factorsinfectionmulti drug resistant organismsMeta-analysis
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：9( 356-363,377 )