Preliminary observation of Bai Rui Capsules in the treatment of patients infected with COVID-19
WANG Xia
LI Jing
TANG Mingze
SHAO Huanhuan
LI Yonggang
Abstract：Objective This study aimed to retrospectively analyze the clinical feasibility and therapeutic effects of Bai Rui Capsules in the treatment of patients infected with the novel coronavirus(COVID-19),providing strong evidence of traditional Chinese medicine treatment to further improve the prognosis of such patients.Methods A total of 282 employees from YOUCARE Pharmaceutical who were infected with the novel coronavirus between November 26th and December 13th,2022,were retrospectively included in this study.According to different treatment regimens,the subjects were divided into 4 groups:the conventional treatment group(40 cases),Bai Rui Capsule monotherapy group(85 cases),Bai Rui Capsule combined with compound paracetamol and amantadine hydrochloride capsules treatment group(95 cases),and Bai Rui Capsule combined with symptomatic treatment group(62 cases).A comparative analysis of the nucleic acid/antigen negative conversion time,the duration of fever,cough resolution time,fatigue resolution time,and the time to amelioration of other symptoms among the four groups of patients was conducted to evaluate the clinical efficacy of Bai Rui Capsules.Results Compared to the conventional treatment group,the 3 groups containing Bai Rui Capsules showed significant advantages in shortening the nucleic acid/antigen negative conversion time,reducing the duration of fever,and time to cough resolution(P＜0.05).The Bai Rui Capsule combined with compound paracetamol and amantadine hydrochloride capsules treatment group showed a significant superiority in shortening the nucleic acid/antigen negative conversion time and reducing the duration of fever compared to the other treatment groups.No adverse reactions related to the use of Bai Rui Capsules were observed during this study.Conclusion The clinical application of Bai Rui Capsules can help shorten the nucleic acid/antigen negative conversion time,reduce the duration of fever and cough disappearance time in patients infected with the novel coronavirus,and has good safety.
Keywords：COVID-19Bai Rui Capsulesintegrated chinese and western medicineefficacy evaluation
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 164-166 )