Research progress of mesenchymal stem cell-derives exosomes on the mechanism of anti-hepatic fibrosis
DONG Xu
YIN Wei
XU Mingxiao
WANG Xinyu
LIANG Xuesong
Abstract：Mesenchymal stem cells are widely sourced,relatively easy to obtain,and function mainly through secreted exosomes.Mesenchymal stem cell-derived exosomes(MSC-exo)play an important role in the transmission of substances and information between cells,and can inhibit liver fibrosis(LF)through various mechanisms,which has a broad application prospect in the field of disease treatment.This article reviews the research of MSC-exo in the mechanism of LF,and provides a new idea for cell-free transplantation of LF.
Keywords：mesenchymal stem cellsexosomeliver fibrosisanti-fibrosiscell-free transplantationmechanismhepatic stellate cellsparacrine effectstissue regenerationregenerative medicine
Publication Date：2023-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 463-468 )