Advance on diagnosis and treatment in children with chronic hepatitis B
ZHANG Min
ZHU Shi-shu
Abstract：Antiviral therapy in children with chronic hepatitis B (CHB) can prevent the progression of liver inflammation and fibrosis, and some of these pediatric patients can be clinically cured. The treatment should start at the period of immune clearance and reactivity, either when the disease progresses or serious complications occur. Currently, interferon and nucleoside analogues can be available for antiviral therapy in children. IFN is a first-line agent for treatment. Nucleoside (acid) analogues (NA) are second-line agents, and the combination of IFN and NA produces potential effects. To maximize the benefit of antiviral therapy in children with CHB, it is vital that to choose the adaptive indication and give individualized treatment.
Keywords：childrenchronic hepatitis Bantiviral therapyinterferonnucleoside (acid) analogues
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 231-236 )