Analysis on influential factors of hepatic venous pressure gradient after esophagogastric variceal bleeding in liver cirrhosis
SHEN Li-jun
DING Peng-peng
HAN Jing-jing
QI Xiao-bao
MA Yu-ming
MA Xue-mei
WU Qin
WU Li-bing
CHU Jin-dong
YU Xiao-li
BI Qian
ZHANG Wen-hui
JIN Bo
LI Han-wei
Abstract：Objective To explorer the influential factors of hepatic venous pressure gradient (HVPG) after esophagogastric variceal bleeding (EVB) in liver cirrhosis. Methods The medical history and clinical data of 178 patients with liver cirrhosis who underwent EVB and their correlation with HVPG measurement in our hospital from January 2015 to July 2017 were retrospectively analyzed. Results The average HVPG value of liver cirrhosis patients who underwent EVB was 16.9 mmHg (1 mmHg=0.133 kPa). HVPG value of viral cirrhosis patients was lower than that of non-viral cirrhosis patients. Patients who had uncommon portosystemic collateral circulations (UPCC) or underwent EVB for more than 3 times might have lower HVPG, while those who had hyperalycemia, hypoalbuminemia, anemia or hepatocellular carcinoma might have higher HVPG, with significant difference (P < 0.05). Multivariant linear regression analysis showed that etiology of cirrhosis, glycosylated hemoglobin level, times of EVB and UPCC could greatly influence HVPG in liver cirrhosis patients after EVB. Conclusions HVPG value increases in liver cirrhosis patients who underwent EVB, and etiology of cirrhosis, glycosylated hemoglobin level, times of EVB and UPCC are regarded the influential factors of HVPG.
Keywords：cirrhosisesophagogastric variceal bleedinghepatic venous pressure gradientinfluential factors
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 140-144 )