Investigations on blood calcium, phosphorus, intact parathyroid hormone level in 61 HIV/AIDS patients after chronic kidney disease maintenance hemodialysis
LAN Ling-xian
SU Chun-xiong
CHEN Wan
CHEN Qiu-xia
HUANG Rui-fen
ZHENG Hui
LIANG Gang
Abstract：ObjectiveTo investigate the mineral metabolism disorder and possible influencing factors in HIV/AIDS patients with maintenance hemodialysis (MHD) in Guangxi area.MethodsSixty-one HIV/AIDS patients treated with MHD for more than 3 months in the Fourth People's Hospital of Nanning (Guangxi AIDS Clinical Treatment Center) from 2011 to 2016 were enrolled in this study, and as the observation group, divided into 2 groups: highly active antiretroviral therapy (HAART) group (n=51) and non-HAART group (n=10 cases). In addition, 30 non-HIV/AIDS patients treated with MHD for more than 3 months were selected as control group. The mineral metabolism indexes including blood calcium, phosphorus and intact varathvroid hormone (iPTH) were determined. Then the related influencing factors were explored.Results Among the 61 HIV/AIDS patients, the control rate of blood calcium, serum phosphorus and iPTH was 47.54% (29/61), 24.59% (15/61) and 21.31% (13/61), respectively. Compared with the control group, the level of blood calcium, phosphorus, iPTH, haemoglobin and ALB levels in the HIV group were significantly lower (P<0.05). However, the levels of serum calcium and iPTH in the HAART group were higher than that in non-HAART group. Serum phosphorus in the HAART group were lower than that in non-HAART group (P<0.05).ConclusionsHIV/AIDS patients in Guangxi area undergoing MHD treatment exhibit unique clinical manifestations of abnormal mineral metabolism. The way of hemodialysis, HAART treatment program and its impact factor need further study.
Keywords：HIV/AIDSchronic kidney diseasemineral metabolismhemodialysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 338-341 )