Clinical and pathological features analysis of 21 patients with idiopathic portal hypertension
MA Xue-mei
REN Hui
JIN Bo
SHEN Li-jun
WU Qin
LU Zheng
CHU Jin-dong
LIU Bo
YU Xiao-li
ZHAO Ping
LI Han-wei
Abstract：Objective To analyze the clinical and pathological features of idiopathic portal hypertension (IPH). Methods The clinical and pathological features of 21 patients with IPH in the 302 Military Hospital of China from January 2012 to December 2016 were retrospectively studied. Results There were 6 male and 15 female patients with a mean age of (38.1±12.7) years old. The main clinical manifestations of IPH were portal hypertension and liver function test had no obvious decline. The main complications were hemorrhage of upper digestive tract and ascites. Liver histopathology of 21 patients showed that the liver plate arrangement was normal, had no pseudolobule formation, portal area expansion, fibrosis surrounding portal vein, different degrees of inflammatory cell infiltration, vascular disturbances, central vein and interlobular vein telangiectasis, liver sinuses dilation, perisinusoidal space fibrosis. Conclusions With sever portal hypertension and mild liver function damage, the diagnosis of IPH patients is depended on liver biopsy. Treatment should be based on prevention and treatment of complications.
Keywords：portal hypertensionidiopathic portal hypertensionpathology
Publication Date：2017-01-01
Pages：4( 168-171 )