Risk factors of esophageal variceal bleeding in patients with hepatitis B cirrhosis
WANG Wan-ming
Abstract：Objective To explore the risk factors of esophageal and gastric varices bleeding in patients with hepatitis B cirrhosis. Methods A total of 165 patients with hepatitis B cirrhosis esophageal varices in our hospital from October 2014 to June 2016 were included in this study. According to the presence of bleeding at the visit day, patients were divided into bleeding group and non-bleeding group. The risk factor of rupture bleeding was analyzed. Results One-way analysis of variance showed that there were no significant differences in the age, gender and white blood cells between the 2 groups (P > 0.05). HGB and PT levels in the bleeding group were obviously higher than those in non-bleeding group, while PLT level was significantly lower (P < 0.05). Patients with liver function Child-Pugh C level, with severe stomach esophagus varicosity, and with moderately severe ascites in the bleeding group were significantly more than those in non-bleeding group, with significant differences in Child-Pugh score, esophageal and gastric varices, and ascites (P < 0.05). Multi-factor analysis showed that liver function Child-Pugh score, platelet count, ascites, portal vein diameter and infection were risk factors for bleeding. Among them ascites was the most important independent risk factor. Conclusions Low Child-Pugh classification of liver function, low platelet count, severe ascites, large portal vein diameter and infection are high risk factors of rupture hemorrhage in patients with hepatitis B cirrhosis, esophageal and gastric varices. Clinical treatment should be given as soon as possible to prevent rupture bleeding.
Keywords：hepatitis B cirrhosisesophageal gastric varicesrupture bleedingrisk factors
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 164-167 )