Clinical characteristics of 45 AIDS patients with cytomegalovirus retinitis
LIANG Jin
Abstract：Objective To investigate the clinical diagnosis and treatment of AIDS patients with cytomegalovirus (CMV) retinitis. Methods Forty-five AIDS patients with CMV retinitis were hospitalized from February 2012 to February 2014 in our hospital. Their clinical data were collected and analyzed retrospectively, including the general information, clinical features, laboratory findings, treatment and outcomes.Results Vision loss and vision blurred were observed in 41 patients (91.11%) and 23 patients (51.11%) , and 3 patients (6.67%) lost their sights. Fundus examination found that there were 31 patients (68.89%) and 5 patients (11.11%) with retinal vasculitis and optic neuritis, respectively, and another 5 patients (11.11%) with retinal detachment. Average CD4+ T lymphocytes were (56.3±12.6) cell/μl. Fifteen patients were CMV-IgM positive (33.33%), and CMV antigen was positive in 18 cases (40%). After the application of tenofovir + lamivudine + efavirenz antiviral treatment, 19 cases (42.22%) were cured, 19 cases (42.22%) were improved, and 7 cases (15.56%) were invalid.Conclusions With the immune function impairment, AIDS patients are easy to merge eye retinitis caused by CMV infection. Impaired vision and visual disturbance are main clinical symptoms. Retinal vasculitis and optic neuritis are common by fundus examination. Active treatment can be obtained remarkable results.
Keywords：AIDScytomegalovirusretinitis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 104-106 )