Clinical characteristics and death risk factors of cirrhosis complicated with hepatorenal syndrome
WANG Wen-ling
SU Xiao-feng
SU Mei
CHAO Hua
LIU Li-chang
WANG Ye
Abstract：Objective To investigate the clinical characteristics and death risk factors in patients who were cirrhosis and complicated with hepatorenal syndrome (HRS).Methods Clinical characteristics were retrospectively analyzed on the 274 cirrhosis patients who were complicated with HRS. The effects of many factors on the prognosis were investigated, including gender, age, type of HRS, complications, underlying diseases, biochemical indexes and treatment.Results Of the 274 patients, 207 were male (75.5%) and 67 were female (24.5%). The average age was 53.39 years old. Forty two cases died among 144 patients with typeⅠHRS, the case fatality rate was 29.2%, and the average survival time was (11.76± 14.13) d. Twelve cases died among 130 patients with typeⅡ HRS. The case fatality rate was 9.2% and the average survival time was (17.41± 17.04) d. Viral hepatitisrelated cirrhosis accounted for 64.2% of the total death, and alcoholic cirrhosis accounted for 25.5%. Female, typeⅠHRS, upper gastrointestinal bleeding, hepatic encephalopathy, peritonitis, hyponatremia were independent risk factors for cirrhosis patients complicated with HRS, and terlipressin treatment was the protective factor.Conclusions There are many death risk factors for the cirrhosis patients complicated with HRS. The prognosis of HRS is poor, and the fatality rate is high. Terlipressin treatment can reduce the risk of death in these patients.
Keywords：hepatorenal syndromecirrhosisclinical characteristicsrisk factorsterlipressin
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 95-98 )