Treatment progress of chronic hepatitis C with direct-acting antivirals in special populations
LI Yuan-yuan
SHI Ji-jing
HUANG Lei
WANG Fu-Sheng
Abstract：With the latest all-oral interferon and ribavirin-free regimens based on direct acting antivirals against the HCV, sustained virological response rates of>90% are achieved, which is equivalent to cure. However, outcomes in special patients with HCV infection tend to be lower and treatment of special patients is often challenging, such as HIV-positive persons, transplant recipients, patients with advanced cirrhosis, renal insufficiency, HBV coinfection, pregnancy, children and older patients. The best way to solve these challenges relies on understanding the potential risks of drug interactions, so as to be of benefits to more special populations with hepatitis C.
Keywords：hepatitis C viruschronic hepatitis Cdirect-acting antiviralsspecial populations
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 70-74 )